In general, studies in adults with CAH have demonstrated impaired BMD [4, 93,94,95,96,97,98,99,100], even though there are exceptions with normal BMD [101, 102], and better than other DSD conditions [103]. Prednisolone may be associated with worse BMD than hydrocortisone [95, 97, 104, 105]. Fractures have not been reported in 3βHSD2D so far but may be increased in CAH in general [93, 95, 97, 99, 100, 103]. Obesity, including severe, has been reported in patients with 3βHSD2D [63, 75], probably due to iatrogenic Cushing syndrome. Chain – several single bets escócia campeonato on irrelevant outcomes. The majority of studies including adults and children with CAH have reported an increased body fat mass assessed by DXA [96, 101, 102, 106, 107], which enables separation between lean mass (which may be increased due to hyperandrogenism) from fat mass.
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