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This study describes the evolution of islet graft function in the early period post-islet transplant using the BETA-2 score. This validated clinical score assessed weekly shows that graft function is established rapidly and increases over the first 4–6 weeks post-transplant before stabilizing. Furthermore, early engraftment estimated by the BETA-2 score as early as 1-week post-transplant is key to predicting longer-term transplant outcomes. Interestingly, our results suggest that it is possible to assess how well a graft will function even before primary graft function is fully established. We compared transplant recipients who achieved insulin independence for at least 1 year after a single transplant to those who remained insulin-dependent and found that the BETA-2 score was significantly higher at 1-week post-transplant among those who achieved insulin independence. We confirmed this in an unselected cohort of islet transplant recipients where a significantly higher BETA-2 score at 1-week was observed among those who achieved insulin independence post-transplant. Como fazer aposta online da mega-sena.Conversas interceptadas pela PF mostram que os suspeitos de vazar a operação que prendeu Ronnie Lessa e Elcio Queiroz também temiam a prisão do político.
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